GlaxoSmithKline
Antibody Discovery Scientist & Engineer
Job Location
Stevenage, United Kingdom
Job Description
Site Name: UK - Hertfordshire - Stevenage
Posted Date: Oct 14 2024
Antibody Discovery Scientist & Engineer
Fixed Term Contract
Biopharm Discovery is a department within GSK's Medicine Design group, part of a state-of-the-art and world-leading R&D Facility. The department is dedicated to the discovery of novel and effective biopharmaceutical medicines. We comprise a number of complementary functions focused on the progression of a portfolio of biopharmaceuticals from initial antibody discovery, expression and characterisation to molecular engineering, biological and physiochemical profiling.
We are currently seeking an enthusiastic and self-motivated Antibody Discovery Scientist. The role will be lab-centric and will involve the identification of antibodies primarily using cutting edge yeast-based platforms, but also more broadly involvement with phage display and other associated techniques. Through 'library design' and molecular engineering you will also be optimising antibodies into therapeutic grade leads towards the ultimate goal of generating first-in-class and best-in-class antibody-based medicines.
This exciting role will give you the opportunity to apply your knowledge and hone your skills as an antibody selections scientist and engineer in a dynamic team of experts working at the early stages of developing world class future medicines. You would also gain exposure to other innovative technologies in use within the team such as B-cell sorting and screening, NGS, In silico-assisted design and AI/ML. Although predominantly lab-based, the role also involves important aspects of verbal and written communication and working within matrix teams across the department on therapeutic antibody programmes.
In this role you will:
Why you?
Basic Qualifications & Skills:
We are looking for professionals with these required skills to achieve our goals:
Preferred Qualifications & Skills:
Please note the following skills are not necessary, just preferred, if you do not have them, please still apply:
Closing Date for Applications: 28th October 2024
Please take a copy of the Job Description, as this will not be available post closure of the advert.
When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.
At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people over the next 10 years. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease. Science and technology are coming together in a way they never have before, and we have strong tech-enabled capabilities that allow us to build a deeper understanding of the patient, human biology and disease mechanisms, and transform medical discovery. We are revolutionising the way we do R&D. We're uniting science, technology and talent to get ahead of disease together.
Find out more:
Our approach to R&D .
Why GSK?
Uniting science, technology and talent to get ahead of disease together.
GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).
Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.
As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class*(*US only).
We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.
Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on Ukdiversity.recruitment@gsk.com or 0808 234 4391.
Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a UK Recruitment FAQ guide. Click the link and scroll to the Careers Section where you will find answers to multiple questions we receive
As you apply, we will ask you to share some personal information which is entirely voluntary. We want to have an opportunity to consider a diverse pool of qualified candidates and this information will assist us in meeting that objective and in understanding how well we are doing against our inclusion and diversity ambitions. We would really appreciate it if you could take a few moments to complete it. Rest assured, Hiring Managers do not have access to this information and we will treat your information confidentially.
Important notice to Employment businesses/ Agencies
GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.
Location: Stevenage, GB
Posted Date: 10/27/2024
Posted Date: Oct 14 2024
Antibody Discovery Scientist & Engineer
Fixed Term Contract
Biopharm Discovery is a department within GSK's Medicine Design group, part of a state-of-the-art and world-leading R&D Facility. The department is dedicated to the discovery of novel and effective biopharmaceutical medicines. We comprise a number of complementary functions focused on the progression of a portfolio of biopharmaceuticals from initial antibody discovery, expression and characterisation to molecular engineering, biological and physiochemical profiling.
We are currently seeking an enthusiastic and self-motivated Antibody Discovery Scientist. The role will be lab-centric and will involve the identification of antibodies primarily using cutting edge yeast-based platforms, but also more broadly involvement with phage display and other associated techniques. Through 'library design' and molecular engineering you will also be optimising antibodies into therapeutic grade leads towards the ultimate goal of generating first-in-class and best-in-class antibody-based medicines.
This exciting role will give you the opportunity to apply your knowledge and hone your skills as an antibody selections scientist and engineer in a dynamic team of experts working at the early stages of developing world class future medicines. You would also gain exposure to other innovative technologies in use within the team such as B-cell sorting and screening, NGS, In silico-assisted design and AI/ML. Although predominantly lab-based, the role also involves important aspects of verbal and written communication and working within matrix teams across the department on therapeutic antibody programmes.
In this role you will:
- Lead the design and execution of experiments towards the identification and optimisation of antibodies using techniques for designing and engineering variants to optimise antibody quality and function within the laboratory.
- Primarily use yeast-based, but also phage-display, selection technologies, potentially combined with B-cell sorting and NGS capabilities.
- Design antibody 'libraries' tailored towards improving certain therapeutic properties of antibodies.
- Represent your 'home team' within matrix groups working towards developing therapeutic antibodies to a variety of 'targets' across a broad spectrum of diseases.
- Prepare and perform verbal and written scientific communications, requiring good organisation as well as a broader scientific knowledge.
- Contribute to some non-lab based workstreams essential to the functioning of cutting-edge antibody discovery department
Why you?
Basic Qualifications & Skills:
We are looking for professionals with these required skills to achieve our goals:
- BSc/MSc in life sciences or equivalent.
- Several years' experience of antibody display and/or directed evolution and associated protein engineering techniques.
- Several years' experience in the lab with molecular biology and associated techniques.
- Expertise within the field to provide subject matter expertise within program teams.
- Excellent analytical and data interpretation skills with the ability to troubleshoot.
- Ability to multitask and work across multiple projects simultaneously.
Preferred Qualifications & Skills:
Please note the following skills are not necessary, just preferred, if you do not have them, please still apply:
- PhD with relevance to the methods and science of protein therapeutics or protein engineering.
- Experience of yeast-display.
- Experience applying AI/ML methods toward protein therapeutics or engineering.
- A level of experience which can be applied to guiding and mentoring more junior scientists.
- Experience of aspects of scientific program leadership.
Closing Date for Applications: 28th October 2024
Please take a copy of the Job Description, as this will not be available post closure of the advert.
When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.
At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people over the next 10 years. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease. Science and technology are coming together in a way they never have before, and we have strong tech-enabled capabilities that allow us to build a deeper understanding of the patient, human biology and disease mechanisms, and transform medical discovery. We are revolutionising the way we do R&D. We're uniting science, technology and talent to get ahead of disease together.
Find out more:
Our approach to R&D .
Why GSK?
Uniting science, technology and talent to get ahead of disease together.
GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).
Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.
As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class*(*US only).
We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.
Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on Ukdiversity.recruitment@gsk.com or 0808 234 4391.
Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a UK Recruitment FAQ guide. Click the link and scroll to the Careers Section where you will find answers to multiple questions we receive
As you apply, we will ask you to share some personal information which is entirely voluntary. We want to have an opportunity to consider a diverse pool of qualified candidates and this information will assist us in meeting that objective and in understanding how well we are doing against our inclusion and diversity ambitions. We would really appreciate it if you could take a few moments to complete it. Rest assured, Hiring Managers do not have access to this information and we will treat your information confidentially.
Important notice to Employment businesses/ Agencies
GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.
Location: Stevenage, GB
Posted Date: 10/27/2024
Contact Information
| Contact | Human Resources GlaxoSmithKline |
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