Scientist I/II, Discovery Biotherapeutics - Multispecifics Engineering

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.

Job Description

Biologics Discovery Sciences at AbbVie is seeking a highly motivated research scientist to join a dynamic team supporting biologics drug discovery and multispecifics engineering. This position will impact projects through the discovery and engineering of biopharmaceutical products. The ideal candidate should have strong experience with a variety of molecular cloning techniques as they relate to multispecifics biologics assembly and knowledge of antibody fragments and mimetics. Other desirable skills include experience with antibody engineering, protein purification expertise, and familiarity with sequence analysis tools. The applicant should be able to analyze, document, and report data. She/he should possess excellent communication skills and be comfortable presenting in group settings.

Qualifications

• Position will be hired based on level of experience.
• BS or MS in biology or related field with 5+ years (BS), or 2+ years (MS) of pharmaceutical and/or relevant experience
• Strong molecular biology skills (e.g. molecular cloning)
• Familiarity with sequence analysis tools (Vector NTI, Geneious, Genedata)
• Experience with __ bacterial and mammalian cell culture
• Experience with protein, biologics, fragments, and multi-specifics purification
• Experience with in vitro analytical techniques for protein characterization (e.g. SEC, MS, DSF)
• Understanding of protein structure and function
• Excellent oral and written communication skills
• Excellent organization skills and the ability to execute on multiple projects simultaneously
• Team player with the ability to operate in a fast-paced multi-disciplinary environment
• Adapt to rapid changes in project priorities and timelines
• Competency with software programs, including MS Excel, Powerpoint, Word

Preferred:

• Experience with antibody engineering, design, and optimization (e.g., humanization, Fc optimization, building multi-specifics)
• Hands-on experience with ELISA, FACS
• Hands-on experience with SEC, HIC, IEX purification of complex biologics utilizing AKTAs
• Utilization of automation (e.g. Hamilton, AssayMap, Kingfisher) equipment in Biologics discovery processes
• Proficiency with mass spectrometry deconvolution and interpretation for complex biologics
• Proficiency with the software programs Geneious, Genedata, PMI, Bioconfirm, Unicorn
• Experience training junior scientists
• Experience with CRO coordination

Significant Work Activities and Conditions:

• Builds strong relationships with peers and cross functionally with partners outside of the team to enable higher performance.
• Learns fast, grasps the “essence” and can change the course quickly where indicated.
• Raises the bar and is never satisfied with the status quo.
• Creates a learning environment, open to suggestions and experimentation for improvement.
• Embraces the ideas of others, nurtures innovation and manages innovation to reality.
• Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8-hour day)

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

• ​This is an on-site opportunity.
• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.​
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​
• This job is eligible to participate in our short-term incentive programs. ​

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

Salary: $71,000 - $134,500